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Clinically, neonatal hemolytic disease is divided into hemolytic disease caused by abo blood group incompatibility and hemolytic disease caused by rh blood group incompatibility. In my country, the most common hemolytic disease of the newborn is the abo blood group system incompatibility. Analyzed, there are several situations: the father has blood type o, and the mother of any blood type will not have neonatal hemolytic disease; the mother of blood type ab, and the father of any blood type will not have neonatal hemolytic disease; the mother is The child is prone to hemolytic disease when he has blood type o and the father is blood type a, b or ab.